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Year Number of Results
2000 1
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2003 4
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2005 8
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2007 8
2008 2
2009 3
2010 2
2011 6
2012 3
2013 4
2014 2
2015 6
2016 2
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78 results

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Page 1
Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer.
Ozen M, Ittmann M. Ozen M, et al. Clin Cancer Res. 2005 Jul 1;11(13):4701-6. doi: 10.1158/1078-0432.CCR-04-2551. Clin Cancer Res. 2005. PMID: 16000564
To determine whether CDC25C activity is altered in prostate cancer, we have examined the expression of CDC25C and an alternatively spliced variant in human prostate cancer samples and cell lines. CDC25C protein is up-regulated in prostate …
To determine whether CDC25C activity is altered in prostate cancer, we have examined the expression of CDC25C and an al …
Targeting CDC25C, PLK1 and CHEK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer.
Al Nakouzi N, Cotteret S, Commo F, Gaudin C, Rajpar S, Dessen P, Vielh P, Fizazi K, Chauchereau A. Al Nakouzi N, et al. Oncotarget. 2014 Feb 15;5(3):667-78. doi: 10.18632/oncotarget.1574. Oncotarget. 2014. PMID: 24525428 Free PMC article.
To further investigate the role of CDC25C, we used inhibitors of the mitotic kinases that regulate CDC25C. ...Our findings identify an important role of LZTS1 through its regulation of CDC25C in Docetaxel resistance in prostate cancer and suggest that …
To further investigate the role of CDC25C, we used inhibitors of the mitotic kinases that regulate CDC25C. ...Our findings ide …
The ethanol extract of Cyperus exaltatus var. iwasakii exhibits cell cycle dysregulation, ERK1/2/p38 MAPK/AKT phosphorylation, and reduced MMP-9-mediated metastatic capacity in prostate cancer models in vitro and in vivo.
Kim H, Hwang B, Cho S, Kim WJ, Myung SC, Choi YH, Kim WJ, Lee S, Moon SK. Kim H, et al. Phytomedicine. 2023 Jun;114:154794. doi: 10.1016/j.phymed.2023.154794. Epub 2023 Mar 30. Phytomedicine. 2023. PMID: 37011419
BACKGROUND: Prostate cancer is the second most common cause of cancer death worldwide in men. ...CONCLUSION: Our results demonstrated the antitumor efficacy of CE against prostate cancer. These findings suggest that CE might be a potential candidate for prostate …
BACKGROUND: Prostate cancer is the second most common cause of cancer death worldwide in men. ...CONCLUSION: Our results demonstrated …
Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
Agarwal C, Tyagi A, Agarwal R. Agarwal C, et al. Mol Cancer Ther. 2006 Dec;5(12):3294-302. doi: 10.1158/1535-7163.MCT-06-0483. Mol Cancer Ther. 2006. PMID: 17172433
We recently reported that gallic acid is a major active agent responsible for grape seed extract activity in DU145 human prostate carcinoma cells. The present study was conducted to examine its efficacy and associated mechanism. ...Together, this is the first report identi …
We recently reported that gallic acid is a major active agent responsible for grape seed extract activity in DU145 human prostate car …
Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells.
Prasad S, Kaur J, Roy P, Kalra N, Shukla Y. Prasad S, et al. Life Sci. 2007 Oct 13;81(17-18):1323-31. doi: 10.1016/j.lfs.2007.07.033. Epub 2007 Sep 15. Life Sci. 2007. PMID: 17936851 Retracted.
Cancer of the prostate gland (PCA) is the most common invasive malignancy and is the second leading cause of cancer-related death in males. ...Thus, it can be concluded that TF acts as an effective anti-proliferative agent by modulating cell growth regulators in prostat …
Cancer of the prostate gland (PCA) is the most common invasive malignancy and is the second leading cause of cancer-related death in …
Integrative Analysis of MicroRNA and Gene Interactions for Revealing Candidate Signatures in Prostate Cancer.
Wei J, Yin Y, Deng Q, Zhou J, Wang Y, Yin G, Yang J, Tang Y. Wei J, et al. Front Genet. 2020 Feb 27;11:176. doi: 10.3389/fgene.2020.00176. eCollection 2020. Front Genet. 2020. PMID: 32180804 Free PMC article.
Thirteen genes (RRM2, ORC6, CDC45, CDKN2A, E2F2, MYBL2, CCNB2, PLK1, FOXM1, CDC25C, PKMYT1, GTSE1, and CDC20) were potentially correlated with prostate cancer based on functional enrichment analyses. ...These findings partially elucidated the dysregulation of gene e …
Thirteen genes (RRM2, ORC6, CDC45, CDKN2A, E2F2, MYBL2, CCNB2, PLK1, FOXM1, CDC25C, PKMYT1, GTSE1, and CDC20) were potentially correl …
Bisphenol A modulates proliferation, apoptosis, and wound healing process of normal prostate cells: Involvement of G2/M-phase cell cycle arrest, MAPK signaling, and transcription factor-mediated MMP regulation.
Song JH, Hwang B, Kim SB, Choi YH, Kim WJ, Moon SK. Song JH, et al. Ecotoxicol Environ Saf. 2023 Jan 1;249:114358. doi: 10.1016/j.ecoenv.2022.114358. Epub 2022 Dec 9. Ecotoxicol Environ Saf. 2023. PMID: 36508820 Free article.
Here, we investigated the effects of BPA on cell proliferation, apoptosis, and the wound healing process using prostate epithelial cells (RWPE-1) and stromal cells (WPMY-1). Observations revealed that BPA induced G2/M cell cycle arrest in both cell types through the ATM-CH …
Here, we investigated the effects of BPA on cell proliferation, apoptosis, and the wound healing process using prostate epithelial ce …
HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate.
Hamid SM, Cicek S, Karamil S, Ozturk MB, Debelec-Butuner B, Erbaykent-Tepedelen B, Varisli L, Gonen-Korkmaz C, Yorukoglu K, Korkmaz KS. Hamid SM, et al. Mol Cell Endocrinol. 2014 Mar 5;383(1-2):38-47. doi: 10.1016/j.mce.2013.12.003. Epub 2013 Dec 8. Mol Cell Endocrinol. 2014. PMID: 24325868
HOXB13 is a homeobox protein that is expressed in normal adult prostate and colon tissues; however, its deregulated expression was evidenced in various malignancies. ...Contrary, siRNA-mediated depletion of HOXB13 expression noticeably increased cyclin levels, stabilized E …
HOXB13 is a homeobox protein that is expressed in normal adult prostate and colon tissues; however, its deregulated expression was ev …
Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.
Ta HQ, Ivey ML, Frierson HF Jr, Conaway MR, Dziegielewski J, Larner JM, Gioeli D. Ta HQ, et al. Cancer Res. 2015 Dec 1;75(23):5093-105. doi: 10.1158/0008-5472.CAN-15-0224. Epub 2015 Nov 16. Cancer Res. 2015. PMID: 26573794 Free PMC article.
Nearly all patients with disseminated prostate cancer initially respond to androgen deprivation therapy (ADT), but virtually all patients will relapse and develop incurable castration-resistant prostate cancer (CRPC). ...In conclusion, we propose that CHK2 is a nega …
Nearly all patients with disseminated prostate cancer initially respond to androgen deprivation therapy (ADT), but virtually all pati …
78 results